Roflumilast Impurity 16
3,5-Dichloro-4-Amino Pyridine
CAS: 228809-78-7
Molecular Formula: C5H4Cl2N2
Roflumilast Impurity 16 - Names and Identifiers
| Name | 3,5-Dichloro-4-Amino Pyridine |
| Synonyms | GenBank AI538353 (9CI) Roflumilast Impurity 16 3,5-dichloropyridin-4-amine 4-amino-3,5-dichloro pyridine 3,5-Dichloro-4-Amino Pyridine 3,5-Dichloro-4-aminopyrimidine 3,5-DICHLORO-4-AMINOPYRIDINE 3,5-DICHLORO-PYRIDIN-4-YLAMINE |
| CAS | 228809-78-7 |
| EINECS | 245-304-6 |
| InChI | InChI=1/C5H4Cl2N2/c6-3-1-9-2-4(7)5(3)8/h1-2H,(H2,8,9) |
Roflumilast Impurity 16 - Physico-chemical Properties
| Molecular Formula | C5H4Cl2N2 |
| Molar Mass | 163.005 |
| Density | 1.497g/cm3 |
| Boling Point | 250.8°C at 760 mmHg |
| Flash Point | 105.5°C |
| Vapor Presure | 0.0212mmHg at 25°C |
| Refractive Index | 1.622 |
| Physical and Chemical Properties | Melting Point: 159 - 161 |
Roflumilast Impurity 16 - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
Roflumilast Impurity 16 - Introduction
3,5-dichloro-4-amino Pyridine (3,5-dichloro-4-amino Pyridine) is an organic compound with the chemical formula C5H4Cl2N2. It is a colorless solid with a weak ammonia aroma. The following is a detailed description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless solid
-Solubility: Soluble in ethanol, dimethyl ether and chloroform, insoluble in water
-Melting point: about 105-108 ° C
-Molecular weight: 162.01g/mol
Use:
-3,5-dichloro-4-amino Pyridine is an important intermediate compound and has a wide range of uses in organic synthesis.
-It is widely used in the synthesis of medicine, dyes and pesticides.
-3,5-dichloro-4-amino Pyridine can be used as a synthetic intermediate for pesticides, such as fungicides and insecticides.
Method:
-3,5-dichloro-4-amino Pyridine has many preparation methods and can be synthesized through various channels.
-The typical preparation method is amination-chlorination reaction, which is prepared by reacting pyridine with an aminating agent and a chlorinating agent.
-The specific experimental conditions can be adjusted according to different documents.
Safety Information:
-3,5-dichloro-4-amino Pyridine needs to be handled with care and following laboratory safe operating procedures.
-It is an irritating compound that may cause irritation to the eyes, skin and respiratory system.
-Wearing suitable personal protective equipment (such as glasses, gloves and protective clothing) is recommended for use.
-Disposal of waste shall comply with local codes and regulations.
Nature:
-Appearance: Colorless solid
-Solubility: Soluble in ethanol, dimethyl ether and chloroform, insoluble in water
-Melting point: about 105-108 ° C
-Molecular weight: 162.01g/mol
Use:
-3,5-dichloro-4-amino Pyridine is an important intermediate compound and has a wide range of uses in organic synthesis.
-It is widely used in the synthesis of medicine, dyes and pesticides.
-3,5-dichloro-4-amino Pyridine can be used as a synthetic intermediate for pesticides, such as fungicides and insecticides.
Method:
-3,5-dichloro-4-amino Pyridine has many preparation methods and can be synthesized through various channels.
-The typical preparation method is amination-chlorination reaction, which is prepared by reacting pyridine with an aminating agent and a chlorinating agent.
-The specific experimental conditions can be adjusted according to different documents.
Safety Information:
-3,5-dichloro-4-amino Pyridine needs to be handled with care and following laboratory safe operating procedures.
-It is an irritating compound that may cause irritation to the eyes, skin and respiratory system.
-Wearing suitable personal protective equipment (such as glasses, gloves and protective clothing) is recommended for use.
-Disposal of waste shall comply with local codes and regulations.
Last Update：2024-04-09 15:17:56
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